Shimadzu LCMS-9030 UHPLC-QTOF
This high resolution tandem quadrupole time-of-flight mass spectrometer is used for a wide range of small molecules and biomolecular applications including proteomics and metabolomics. The instrument has a mass range of up to 40,000 m/z, resolution of >30,000 FWMH, and high mass accuracy typically within 5 ppm error. In addition to standard MS and MS/MS, the following acquisition modes are also available: DDA, DIA, SIM, and MRM. The instrument is equipped with an ESI source and has an optional DUIS source which combines ESI and APCI capabilities. The UHPLC system by default operates with a water/acetonitrile or water/methanol mobile phase. A Shimadzu Nexcol C18 1.8 um column is available for general use. Column bypass is commonly used for samples that do not require LC separation.
Bruker Microflex LRF MALDI TOF
This MALDI TOF can be used for the analysis of a broad range
of compounds including small molecules, peptides, proteins, nucleic
acids, and synthetic polymers. The Microflex accepts 96 spot target
plates. The matrix assisted laser desorption ionization (MALDI)
source operates with a 60 Hz nitrogen laser at 337 nm. The instrument
has a mass range of up to 20,000 m/z in reflectron mode or 500,000
m/z in linear mode. Additionally the instrument is capable of mass
spectral imaging. Polytools software is available for the analysis of
Waters GCT Premier GC TOF
This high resolution Time-of-Flight mass spectrometer is primarily used for small organic analytes and low polarity materials. The instrument is equipped with electron ionization (EI), chemical ionization (CI), and field ionization/field desorption (FI/FD) ion sources. This instrument has a mass range up to m/z 800 in EI, CI, and FI modes and up to m/z 4000 in FD mode. Accurate mass measurement (<3 mDa) for elemental composition confirmation is available in EI and CI modes. The GCT Premier employs an Agilent 7890 A gas chromatograph and Agilent 7683 B autosampler in EI, CI, and FI modes.